MINING NATURE FOR BIOACTIVE SMALL MOLECULES

A new age of small molecule discovery from nature

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Cutting-edge natural product small molecule discovery

Natural products, shaped by billions of years of evolution, serve as nature's optimized solutions with unique biological activities. They represent an astonishing chemical diversity and have been the greatest source of discovery in pharmaceuticals and agricultural fields. However, their immense diversity and chemical novelty pose challenges to their discovery process. Using methods developed by our esteemed scientific team, Chemia Biosciences's discovery platform integrates genomics and metabolomics for rapid and accurate discovery of natural products with novel chemistry and mechanisms of action

Scientists working in laboratory

About Us

Transforming Nature into New Medicines

Chemia Biosciences spun out of Carnegie Mellon University, School of Computer Science. Chemia's platform is based on cutting-edge methods developed by Hosein Mohimani, PhD, and Bahar Behsaz, PhD. Cheima Bio's platform finds novel small molecules that can function as drug leads targeting drug-resistant and orphan diseases, and new crop protection molecules. Chemia's platform has already led to the discovery of multiple novel bioactive molecules.

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How We Do it

About Services

Chemia Bio's proprietary platform combines AI-enabled genome mining with our one-of-a-kind metabolomics search engine for discovering novel small molecule drugs. Our cutting-edge methods can rapidly search through thousands of microbial organisms to discover novel small molecules undetectable by other methods. Using our proprietary genomics library and AI algorithms, we can predict the potential of the microbes for generating novel compounds with desirable properties and bioactivities. Our unique metabolomics search engine then can detect the molecules with novel chemistry and potentially novel modes of action against targets of interest. Using this technology, Chemia team has discovered numerous small molecules bioactive against various targets.

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Applications

Animal Health

Drug Discovery

Agriculture

Pipeline

Program
Discovery
Optimization
IND-Enabling
Clinical
Edaphochelin A
CHM-1092
CHM-1035
CHM-495
CHM-971
CHM-1222

Partners and Collaborators

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